program nanotme 2021

 23-24 September, Enschede The Netherlands                 

 Thursday 23 September 2021

Dutch time (CEST)


09:00

Welcome speech

Jai Prakash and Yuval Shaked

09:15

Keynote lecture

Emile Voest

The battle between tumor and immune cells in cancer patients: New insights

Session 1: Tumor Immune microenvironment - Session chair: Yuval Shaked

09:50

Karin de Visser

Immune Complexity of Metastatic Breast Cancer: Towards personalized immune intervention strategies

10:15

Xiaoyuan (Shawn) Chen

Modulating Immunosuppressive Tumor Environment with Nanomedicine

10:40

Zvika Granot

Neutrophil-specific targeting as cancer immunotherapy

11:05

Break

Session 2: Nanomedicine and TME - Session chair: Zvika Granot

11:30

Ronit Satchi-Fainaro

Fighting p-selectin-expressing glioblastoma in 3 dimensions

11:55

Veronique Preat

Nanomedicine to target the microenvironment of colorectal cancer and glioblastoma

12:20

Maria Vicent

Polypeptide-based nanoconjugates as versatile modulators of tumor microenvironment

12:45

Lunch

Breakrooms for discussion and networking

Session 3: Short talks - Session chair: Twan Lammers

13:45

Triantafyllos Stylianopoulos

Tumor microenvironment normalization with nanomedicine and metronomic therapy: implications for immunotherapy

13:57

Nora Dekoning

Nanoparticles as delivery vehicles for gene transport to the tumor microenvironment and endothelial cells

14:09

Marcel Heinrich

Mimicking blood vessel collapse in pancreatic cancer using 3d engineered vascularized tissues

14:21

Dave S.B. Hoon

Spatial analysis of TME microglia in immune checkpoint inhibitor resistant and non-treated melanoma brain metastasis

14:33

Andrea Abaurrea

Stromal oncostatin m axis promotes breast cancer progression

14:45

Ninh (Irene) La-Beck

Targeting tumor immunologic milieu with liposomal amino-bisphosphonates

15:00

Break

15:15

Publishing in Nature

Anna Dart - Nature publishing

Publishing in the Nature portfolio journals

Session 4: Nanomedicine and TME - Session chair: Jai Prakash

15:45

Mansoor Amiji

Modulation of the Tumor Microenvironment with microrna Nano-Vectors

16:10

Natalie Artzi

Biomaterials-aided combination immunotherapy

16:35

Keynote lecture

Leaf Huang

Nano Intervention of Tumor Microenvironment to Improve Therapy

17:10

Closure day 1


friday 24 september 2021

Session 5: Tumor stroma and ECM - Session chair: Jai Prakash

09:00

Arne Östman

Identification of novel caf-subsets in colorectal and lung cancer with diffferential associations to driver mutations, immune features and outcome

09:25

Erik Sahai

STING and IRF3 in stromal fibroblasts enable sensing of genomic stress in cancer cells to undermine oncolytic viral therapy

09:50

Luuk Hawinkels

Enhanced antigen cross-presentation in human colorectal cancer-associated fibroblasts through upregulation of the lysosomal protease Cathepsin S

10:15

Jen Morton

Targeting the Immune Microenvironment in Pancreatic Cancer

Session 6: Targeting metastasis - Session chair: Luuk Hawinkels

10:40

Isaac Witz

A vicious cycle of melanoma-microglia crosstalk promotes brain metastasis

11:05

Janine Erler

Targeting the metastatic niche

11:30

Break

11:45

Rajkumar Savai

Lung microenvironmental niche in cancerogenesis: What do fibrocytes have to offer?

Session 7: Short talks - Session chair: Helena Florindo

12:05

Fotios  Mbekris

Dexamethasone normalizes tumor microenvironment and enhances efficacy of cisplatin-loaded nanocarrier in cancer

12:17

Lee Shaashua-Berger

BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking CLU+ CAFs with HSF1 signaling

12:29

Claudia Martins

Novel docetaxel nanomedicine meets the tumor microenvironment to defeat glioblastoma

12:41

Shimrit Mayer

Characterizing fibroblast-macrophage signaling circuits in the tumor microenvironment

12:53

Lunch

Breakrooms for discussion and networking

Session 8: Nano-targeted therapies and imaging of TME & Pitches - Session chair: Alberto Gabizon

13:30

Helena Florindo

Multifunctional nanovaccines for vascular regulation of antitumor immunity

13:55 


Marcelle Machluf

Nanoghost: Harnessing the power of stem cell to target and inhibit cancer growth

14:20

Pitches - 27 each 1.5 min + 10 min discussion



  1. Sofia Avnet
  2. Alessia Bacci
  3. Iker Badiola
  4. Karina Benderski
  5. Madeleine Benguigui
  6. Paz Boix-Montesinos
  7. Kiana Buttiens
  8. Cristina Casadidio
  9. Maksoudian Christy
  10. Tianjiao Chu
  11. Francesca Corsi
  12. Asmaa Said Elshafei
  13. Evelien Hesemans
  14. Mukaddes Izci
  15. Anu Thomas  Koikalethu
  16. Xanthippi  Koutsoumpou
  17. Deby Mardhian
  18. Dina Morein
  19. Prerna Nepali
  20. Miranda Panagi
  21. Kunal Pednekar
  22. Katarzyna Poleszak
  23. Alexander Ries
  24. Karolin Römhild
  25. Neshat  Saffarzadeh
  26. Antoni Serrano Martí
  27. Avital Vorontsova

15:15

Break



Session 9: Nano-targeted therapies and imaging of TME - Session chair: Yuval Shaked

15:30

Michele De Palma

Mechanisms of microenvironmental tumor resistance to immune checkpoint blockade

15:55

Miles Miller

Imaging the impacts of cellular phosphosignaling on nanotherapy action in tumors

16:20

Twan Lammers

Pharmacological and Physical Priming of the Tumor Microenvironment

16:45

Paolo Decuzzi

Hierarchically-structured polymeric drug delivery systems for cancer management 

17:10

Prizes and Closure